What is Siromus 1mg?
Siromus 1mg is an immuno-suppressant, which in combination with other medications is used during kidney transplant to prevent rejection. It is also used to coat coronary stents and treat lymphangioleiomyomatosis. This medicine is is usually taken once daily, but consult your doctor regarding the right dosage. It is available as a chewing tablet as well as in liquid form.
Uses of Siromus 1 mg Tablet
- Organ Transplant – Rejection Prophylaxis
This medicine is used to prevent the rejection of an organ transplant.
- Pulmonary lymphangioleiomyomatosis
This medicine is used in the treatment of Pulmonary lymphangioleiomyomatosis, a condition which affects the lungs of especially women of childbearing ages, leading to progressive lung dysfunction.
How to use Siromus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. sirolimus 1mg may be taken with or without food, but it is better to take it at a fixed time.
How Siromus Tablet works
Siromus 1 mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.
Major & minor sirolimus side effects are here
- Unusual bleeding or bruising
- Cracked or scaly skin
- Abdominal and stomach pain
- Constipation or diarrhea
- Upper respiratory tract infection
- Urinary tract infection
- Difficulty in breathing
- Nervousness and confusion
If you miss a dose of Siromus 1mg Tablet, take the missed dose as soon as you remember. If sirolimus dosage is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Seek emergency medical treatment or contact a doctor immediately in case of an overdose.
Warnings for special population
Pregnancy – This medicine is not recommended for use in pregnant women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.
Breast-feeding – This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Use in pediatrics – This medicine is not recommended for use in children less than 13 years of age.
Blood pressure – This medicine may cause an increase in blood pressure. Close monitoring of blood pressure is necessary during treatment with this medicine.
Use of contraception – Women of childbearing age are advised to use effective contraception prior to, during, and for 12 weeks following treatment with this medicine to avoid pregnancy. This medicine may cause serious side effects in the fetus.
Expert advice for Siromus Tablet
You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
sirolimus 1mg increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer).
Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus. Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
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